Restoration of neuronal connectivity after a lesion of the central nervous system, such as spinal cord injury, is one of the greatest challenges in modern medicine. In particular, the accumulation of factors inhibiting the growth of axons at the site of injury is a major obstacle to the improvement of structural and thus functional.
We previously investigated prenylflavonoids group derived from hops to their capacity to promote neuroregeneration. We identified a molecule called ENDF1 a very powerful tool to increase the re-growth and branching of neurites of dorsal root ganglion neurons in culture in promoting the growth substrate.
In this study, we investigated the capacity ENDF1 to promote regeneration of rat dorsal root ganglion neurons in vitro in the presence of the three main components of the extracellular matrix that acts as an inhibitor of axon growth: semaphorin 3A, Ephrin A4 and mixed with chondroitin sulfate proteoglycans. We reported that ENDF1 application significantly promoted the percentage of sensory neurons were able to regrow their neurites irrespective of their presence inhibitor, and this to an extent similar to that obtained after NGF treatment. In addition, the greatly enhanced ENDF1 total neurite length and complexity of neurites extending from neurons challenged with axon growth inhibitors.
Although the effects of NGF and ENDF1 on regeneration of neurons was similar, ENDF1 activity is not mediated by signaling through TrkA receptor, suggesting that each molecule acts via different signaling pathways. Additionally, ENDF1 not degrade cofilin phosphorylation, downstream effectors associated regeneration of RhoA / ROCK signaling pathway. Therefore, ENDF1 is pro-neuroregenerative potent factor that may help in identifying new efficient targets for regenerative therapies of the nervous system.
DAB Buffer, 10X For use with DAB Staining System for HRPO |
|
MBS639268-50mL |
MyBiosource |
50mL |
EUR 280 |
DAB Buffer, 10X For use with DAB Staining System for HRPO |
|
MBS639268-5x500mL |
MyBiosource |
5x500mL |
EUR 2090 |
UltraTek HRP Anti-Polyvalent (DAB) Staining System |
|
AMF080 |
ScyTek Laboratories |
70 Slides |
EUR 70.71 |
SensiTek HRP Anti-Polyvalent (DAB) Staining System |
|
AEM080 |
ScyTek Laboratories |
70 Slides |
EUR 61.72 |
DAB Enhancer for ampliying and darkening DAB stains in IHC staining, 60 ml (Large volume) |
|
NB308 |
Innovex |
60 ml |
EUR 435 |
DAB Enhancer for ampliying and darkening DAB stains in IHC staining, 30 ml (Small volume) |
|
NB308-30 |
Innovex |
30 ml |
EUR 285 |
DAB Stable Liquid Substrate 50X Concentrate, 0.0694mM Staining System for HRPO |
|
MBS639197-100mL |
MyBiosource |
100mL |
EUR 715 |
DAB Stable Liquid Substrate 50X Concentrate, 0.0694mM Staining System for HRPO |
|
MBS639197-10mL |
MyBiosource |
10mL |
EUR 300 |
DAB Stable Liquid Substrate 50X Concentrate, 0.0694mM Staining System for HRPO |
|
MBS639197-25mL |
MyBiosource |
25mL |
EUR 380 |
DAB Stable Liquid Substrate 50X Concentrate, 0.0694mM Staining System for HRPO |
|
MBS639197-5x100mL |
MyBiosource |
5x100mL |
EUR 3075 |
STAT-Q Rabbit DAB KIT for staining all Rabbit antibodies, 350 plus slides |
|
NB314KLRD-20 |
Innovex |
20 ml kit |
EUR 645 |
STAT-Q Goat DAB KIT for staining all Goat primary antibodies, 350 plus slides |
|
NB314KLGD-20 |
Innovex |
20 ml kit |
EUR 645 |
PI Staining Kit |
|
abx097208-1Kit |
Abbexa |
1 Kit |
EUR 276 |
|
|
HE staining Kit |
|
MBS2567140-100mL |
MyBiosource |
100mL |
EUR 255 |
HE staining Kit |
|
MBS2567140-10mL |
MyBiosource |
10mL |
EUR 120 |
HE staining Kit |
|
MBS2567140-50mL |
MyBiosource |
50mL |
EUR 195 |
HE staining Kit |
|
MBS2567140-5x100mL |
MyBiosource |
5x100mL |
EUR 1120 |
PI Staining Kit |
|
MBS826722-01mL |
MyBiosource |
0.1mL |
EUR 140 |
PI Staining Kit |
|
MBS826722-5x01mL |
MyBiosource |
5x0.1mL |
EUR 550 |
DAPI Staining Kit |
|
abx097206-100l |
Abbexa |
100 µl |
EUR 162.5 |
DAPI Staining Kit |
|
abx097206-1Kit |
Abbexa |
1 Kit |
EUR 276 |
|
|
DAPI Staining Kit |
|
abx097206-1ml |
Abbexa |
1 ml |
Ask for price |
DAPI Staining Kit |
|
abx097206-200l |
Abbexa |
200 µl |
Ask for price |
DAPI Staining Kit |
|
MBS826728-01mL |
MyBiosource |
0.1mL |
EUR 140 |
DAPI Staining Kit |
|
MBS826728-5x01mL |
MyBiosource |
5x0.1mL |
EUR 550 |
STAT-Q Rat Adsorbed DAB KIT for staining Mouse antibodies-on-Rat tissues 250 plus slides kit |
|
NB314RAK-DAB |
Innovex |
200-250 slides |
EUR 745 |
Slides Staining Jar |
|
K01 |
GuideMedLab |
For 5 PCS |
Ask for price |
Slides Staining Jar |
|
K02 |
GuideMedLab |
For 10 PCS |
Ask for price |
STAT-Q Mouse Adsorbed DAB KIT for staining Rat antibodies-on-Mouse tissues 250 plus slide kit |
|
NB314MAK-DAB |
Innovex |
200-250 slides |
EUR 695 |
DNA Staining Reagent |
|
abx299713-100g |
Abbexa |
100 µg |
Ask for price |
DNA Staining Reagent |
|
abx299713-20g |
Abbexa |
20 µg |
EUR 300 |
DNA Staining Reagent |
|
abx299713-50g |
Abbexa |
50 µg |
Ask for price |
Cell Staining Buffer |
|
E16FXP005 |
EnoGene |
500 ml |
EUR 40 |
|
Description: Available in various conjugation types. |
Cell Staining Buffer |
|
MBS2567126-100mL |
MyBiosource |
100mL |
EUR 90 |
Cell Staining Buffer |
|
MBS2567126-200mL |
MyBiosource |
200mL |
EUR 100 |
Cell Staining Buffer |
|
MBS2567126-500mL |
MyBiosource |
500mL |
EUR 125 |
Cell Staining Buffer |
|
MBS2567126-5x500mL |
MyBiosource |
5x500mL |
EUR 545 |
Cell Staining Buffer |
|
MBS679239-500mL |
MyBiosource |
500mL |
EUR 185 |
Cell Staining Buffer |
|
MBS679239-5x500mL |
MyBiosource |
5x500mL |
EUR 675 |
Cell Staining Buffer |
|
MBS679240-100mL |
MyBiosource |
100mL |
EUR 130 |
Cell Staining Buffer |
|
MBS679240-5x100mL |
MyBiosource |
5x100mL |
EUR 435 |
Cell Staining Buffer |
|
MBS679241-250mL |
MyBiosource |
250mL |
EUR 145 |
Cell Staining Buffer |
|
MBS679241-5x250mL |
MyBiosource |
5x250mL |
EUR 515 |
Cell Staining Buffer |
|
GT17982 |
Sony |
500 mL |
Ask for price |
|
|
Slides Staining Rack |
|
K06 |
GuideMedLab |
For 30 PCS |
Ask for price |
Slides Staining Rack |
|
K07 |
GuideMedLab |
For 24 PCS |
Ask for price |
DAPI Staining Solution |
|
MBS176580-10mL |
MyBiosource |
10mL |
EUR 115 |
DAPI Staining Solution |
|
MBS176580-50mL |
MyBiosource |
50mL |
EUR 135 |
DAPI Staining Solution |
|
MBS176580-5x50mL |
MyBiosource |
5x50mL |
EUR 450 |
STAT-Q Multivalent DAB KIT for staining Mouse, Rat and Rabbit antibodies, 350 slides kit (Small size Kit) |
|
NB314KLD-20 |
Innovex |
300 slide kit |
EUR 655 |
jetBlue Protein Staining Solution |
|
MBS402061-20mL |
MyBiosource |
20mL |
EUR 165 |
jetBlue Protein Staining Solution |
|
MBS402061-500mL |
MyBiosource |
500mL |
EUR 210 |
Wright Staining Solution |
|
K1182-100 |
ApexBio |
100ml |
EUR 40 |
|
Description: Cell Biology|Staining Solution |
Wright Staining Solution |
|
K1182-500 |
ApexBio |
500ml |
EUR 64 |
|
Description: Cell Biology|Staining Solution |
SpectBlue Protein Staining Reagent |
|
8019011 |
Dakewe Biosci |
250 mL |
Ask for price |
STAT-Q Multivalent DAB KIT for staining Mouse, Rat and Rabbit antibodies, 1000 plus slides (Large size kit) |
|
NB314KLD |
Innovex |
1000 slides |
EUR 895 |
ELVIS ID Staining Kit |
|
SK-ELVIS-100 |
Quidel |
100 Tests |
Ask for price |
ELVIS ID Staining Kit |
|
SK-ELVIS-1000 |
Quidel |
1000 Tests |
Ask for price |
ELVIS ID Staining Kit |
|
SK-ELVIS-200 |
Quidel |
200 Tests |
Ask for price |
ELVIS ID Staining Kit |
|
SK-ELVIS-500 |
Quidel |
500 Tests |
Ask for price |
Colloidal Protein Staining Solution |
|
51581 |
Sisco Laboratories |
100 ml |
EUR 25.5 |
|
|
|
Description: Part B |
Hoechst 33342 Staining Kit |
|
abx097207-100l |
Abbexa |
100 µl |
EUR 162.5 |
Hoechst 33342 Staining Kit |
|
abx097207-1Kit |
Abbexa |
1 Kit |
EUR 276 |
|
|
Hoechst 33342 Staining Kit |
|
abx097207-1ml |
Abbexa |
1 ml |
Ask for price |
Hoechst 33342 Staining Kit |
|
abx097207-200l |
Abbexa |
200 µl |
Ask for price |
Hoechst 33342 Staining Kit |
|
MBS826727-01mL |
MyBiosource |
0.1mL |
EUR 140 |
Hoechst 33342 Staining Kit |
|
MBS826727-5x01mL |
MyBiosource |
5x0.1mL |
EUR 550 |
DNA STAINING AGENT (1ML) |
|
NOVELJUICE |
Consort |
each |
EUR 80 |
Cartilage Staining Solution |
|
MBS355813-100mL |
MyBiosource |
100mL |
EUR 185 |
Cartilage Staining Solution |
|
MBS355813-5x100mL |
MyBiosource |
5x100mL |
EUR 530 |
Hematoxylin staining Buffer |
|
MBS2567138-15mL |
MyBiosource |
15mL |
EUR 125 |
Hematoxylin staining Buffer |
|
MBS2567138-50mL |
MyBiosource |
50mL |
EUR 190 |
Hematoxylin staining Buffer |
|
MBS2567138-5mL |
MyBiosource |
5mL |
EUR 95 |
Hematoxylin staining Buffer |
|
MBS2567138-5x50mL |
MyBiosource |
5x50mL |
EUR 815 |
Cell Cycle Staining Kit |
|
KTA2020-100T |
Abbkine |
100 T |
EUR 119 |
|
Description: Abbkine Cell Cycle Staining Kit provides a convenient and accurate determination of the percentage of cells in each phase of the cell cycle. |
Cell Cycle Staining Kit |
|
KTA2020-50T |
Abbkine |
50 T |
EUR 69 |
|
Description: Abbkine Cell Cycle Staining Kit provides a convenient and accurate determination of the percentage of cells in each phase of the cell cycle. |
Cell Cycle Staining Kit |
|
KTA2020-each |
Abbkine |
each |
Ask for price |
Cell Cycle Staining Kit |
|
MBS9718793-100Tests |
MyBiosource |
100Tests |
EUR 225 |
Cell Cycle Staining Kit |
|
MBS9718793-500Tests |
MyBiosource |
500Tests |
EUR 355 |
Cell Cycle Staining Kit |
|
MBS9718793-50Tests |
MyBiosource |
50Tests |
EUR 195 |
Cell Cycle Staining Kit |
|
MBS9718793-5x500Tests |
MyBiosource |
5x500Tests |
EUR 1580 |
HISTOCHEMISTRY STAINING TRAY |
|
AT-12 |
IBI Scientific |
12 PLACE - BLACK LID |
EUR 226.1 |
HISTOCHEMISTRY STAINING TRAY |
|
AT-24 |
IBI Scientific |
24 PLACE - BLACK LID |
EUR 342.21 |
HISTOCHEMISTRY STAINING TRAY |
|
ATC-12 |
IBI Scientific |
12 PLACE - CLEAR LID |
EUR 226.1 |
HISTOCHEMISTRY STAINING TRAY |
|
ATC-24 |
IBI Scientific |
24 PLACE - CLEAR LID |
EUR 342.21 |
Exosome fluorescent staining |
|
S104 |
101Bio |
- |
EUR 800 |
PI / RNase Staining Buffer |
|
abx090619-100l |
Abbexa |
100 µl |
EUR 162.5 |
PI / RNase Staining Buffer |
|
20-abx090619 |
Abbexa |
-
Ask for price
-
Ask for price
|
|
|
|
PI / RNase Staining Buffer |
|
abx090619-1ml |
Abbexa |
1 ml |
Ask for price |
PI / RNase Staining Buffer |
|
abx090619-200l |
Abbexa |
200 µl |
EUR 200 |
Live NucRed staining kit |
|
EGY069 |
EnoGene |
>100T |
EUR 210 |
PI / RNase Staining Buffer |
|
MBS355225-100Tests |
MyBiosource |
100Tests |
EUR 255 |
PI / RNase Staining Buffer |
|
MBS355225-50Tests |
MyBiosource |
50Tests |
EUR 215 |
PI / RNase Staining Buffer |
|
MBS355225-5x100Tests |
MyBiosource |
5x100Tests |
EUR 845 |
Live NucRed staining kit |
|
MBS8584964-100Tests |
MyBiosource |
100Tests |
EUR 310 |
Live NucRed staining kit |
|
MBS8584964-5x100Tests |
MyBiosource |
5x100Tests |
EUR 1405 |
Lectin Gold Staining Kit |
|
LGS-01 |
EY Laboratories |
1 mg |
Ask for price |
|
Description: Lectin Gold Staining Kit.
Kit Contents: 1mg pure Limax flavus (LFA), 5mg each of Canavalia ensiformis (Con A) and Triticum vulgare (WGA), 1ml each of Horseradish Peroxidase, Ovomucoid, Fetuin, Arachis hypogaea (PNA), Dolichos biflorus (DBA), and Ulex europaeus (UEA-I), all labeled with 15nm colloidal gold, 10ml each of the required inhibitory carbohydrates for each lectin, appropriate buffers, and 1 Silver Enhancement Kit.
Product volume may vary.
With the exception of Diagnostic Microbiology Products all biochemicals described are for research use only. The biochemical reagents are not designed for use in therapeutic or diagnostic applications. We are unable to ship to individuals. Please place all orders through an established firm or institution. Nothing disclosed is to be construed as a recommendation to use our products in violation of any patents. All research products are offered without warranty or guarantee, since the ultimate condition of use and the variability in material handling are beyond our control. |
EzWay Protein-Silver Staining Kit |
|
K14040D |
KOMA BIOTECH |
20A |
EUR 188 |
|
Description: https://komabiotech.co.kr/labiskoma/datasheet/K14040D-korean.pdf |
ProsiBlue Gel Staining Solution |
|
P7300-050 |
GenDepot |
500ml |
EUR 102 |
7-AAD Staining Solution |
|
MBS669126-200Tests |
MyBiosource |
200Tests |
EUR 145 |
7-AAD Staining Solution |
|
MBS669126-5x200Tests |
MyBiosource |
5x200Tests |
EUR 655 |
Ponceau S Protein Staining Solution |
|
PS003-B500ML |
Bio-Helix |
500 ml |
EUR 25 |
Live NucGreen staining kit |
|
EGY068 |
EnoGene |
>100T |
EUR 210 |
Dead NucGreen staining kit |
|
EGY070 |
EnoGene |
>100T |
EUR 210 |
Live NucGreen staining kit |
|
MBS8584963-100Tests |
MyBiosource |
100Tests |
EUR 310 |
Live NucGreen staining kit |
|
MBS8584963-5x100Tests |
MyBiosource |
5x100Tests |
EUR 1405 |
Dead NucGreen staining kit |
|
MBS8584965-100Tests |
MyBiosource |
100Tests |
EUR 310 |
Dead NucGreen staining kit |
|
MBS8584965-5x100Tests |
MyBiosource |
5x100Tests |
EUR 1405 |
Nimble Juice (Protein Staining Reagent) |
|
NJ001-0001 |
GeneDireX |
1 mL |
Ask for price |
Nimble Juice (Protein Staining Reagent) |
|
NJ001-0010 |
GeneDireX |
10 mL |
Ask for price |
GEL STAINING/INCUBATION BOX |
|
SB-10 |
IBI Scientific |
LIGHT SHIELDING |
EUR 94.44 |
Ponceau S Staining Solution |
|
41640009-1 |
Bio-WORLD |
500 mL |
EUR 53.1 |
|
|
Ponceau S Staining Solution |
|
41640009-2 |
Bio-WORLD |
1 L |
EUR 76.5 |
|
|
Ponceau S Staining Solution |
|
B7778-100000 |
ApexBio |
100 g |
EUR 77.6 |
|
|
|
Description: Others|Reagents |
Ponceau S Staining Solution |
|
B7778-50000 |
ApexBio |
50 g |
EUR 52.8 |
|
|
|
Description: Others|Reagents |
Giemsa Staining Solution (10X) |
|
K1181-100 |
ApexBio |
100ml |
EUR 40 |
|
Description: Cell Biology|Staining Solution |
Giemsa Staining Solution (10X) |
|
K1181-500 |
ApexBio |
500ml |
EUR 64 |
|
Description: Cell Biology|Staining Solution |
Ponceau S Staining Solution |
|
MBS355693-100mL |
MyBiosource |
100mL |
EUR 180 |
Ponceau S Staining Solution |
|
MBS355693-5x100mL |
MyBiosource |
5x100mL |
EUR 500 |
Sirius Red Staining Solution |
|
MBS355815-100mL |
MyBiosource |
100mL |
EUR 195 |
Sirius Red Staining Solution |
|
MBS355815-5x100mL |
MyBiosource |
5x100mL |
EUR 570 |
Ponceau S Staining Solution |
|
PW005 |
Bio Basic |
100ml |
EUR 82.97 |
|
|
AO/PI Double Staining Kit |
|
K2238-100 |
ApexBio |
100T |
EUR 40 |
|
Description: Cell Biology|Cell Apoptosis |
AO/PI Double Staining Kit |
|
K2238-500 |
ApexBio |
500T |
EUR 120 |
|
Description: Cell Biology|Cell Apoptosis |
Neutral Red Staining Solution |
|
K1185-100 |
ApexBio |
100ml |
EUR 40 |
|
Description: Cell Biology|Staining Solution |
CellSurface FLOW Staining Kit |
|
MBS668926-1Kit |
MyBiosource |
1Kit |
EUR 200 |
CellSurface FLOW Staining Kit |
|
MBS668926-5x1Kit |
MyBiosource |
5x1Kit |
EUR 900 |
Propidium Iodide (PI) Staining Kit |
|
abx097208-100l |
Abbexa |
100 µl |
EUR 162.5 |