Microporator

Very low volume electroporation devices for Jurkats and DRG neurons.

The Prenylflavonoid ENDF1 Overrules Central Nervous System Growth Inhibitors and Facilitates Regeneration of DRG Neurons.

Restoration of neuronal connectivity after a lesion of the central nervous system, such as spinal cord injury, is one of the greatest challenges in modern medicine. In particular, the accumulation of factors inhibiting the growth of axons at the site of injury is a major obstacle to the improvement of structural and thus functional.

We previously investigated prenylflavonoids group derived from hops to their capacity to promote neuroregeneration. We identified a molecule called ENDF1 a very powerful tool to increase the re-growth and branching of neurites of dorsal root ganglion neurons in culture in promoting the growth substrate.

In this study, we investigated the capacity ENDF1 to promote regeneration of rat dorsal root ganglion neurons in vitro in the presence of the three main components of the extracellular matrix that acts as an inhibitor of axon growth: semaphorin 3A, Ephrin A4 and mixed with chondroitin sulfate proteoglycans. We reported that ENDF1 application significantly promoted the percentage of sensory neurons were able to regrow their neurites irrespective of their presence inhibitor, and this to an extent similar to that obtained after NGF treatment. In addition, the greatly enhanced ENDF1 total neurite length and complexity of neurites extending from neurons challenged with axon growth inhibitors.

Although the effects of NGF and ENDF1 on regeneration of neurons was similar, ENDF1 activity is not mediated by signaling through TrkA receptor, suggesting that each molecule acts via different signaling pathways. Additionally, ENDF1 not degrade cofilin phosphorylation, downstream effectors associated regeneration of RhoA / ROCK signaling pathway. Therefore, ENDF1 is pro-neuroregenerative potent factor that may help in identifying new efficient targets for regenerative therapies of the nervous system.

DAB Buffer, 10X For use with DAB Staining System for HRPO
MBS639268-50mL 50mL
EUR 280

DAB Buffer, 10X For use with DAB Staining System for HRPO
MBS639268-5x500mL 5x500mL
EUR 2090

SensiTek HRP Anti-Mouse (DAB) Staining System
AEA080 70 Slides
EUR 55.28

UltraTek HRP Anti-Mouse (DAB) Staining System
AKA080 70 Slides
EUR 61.72

SensiTek HRP Anti-Rabbit (DAB) Staining System
AEI080 70 Slides
EUR 55.28

UltraTek HRP Anti-Rabbit (DAB) Staining System
AKC080 70 Slides
EUR 61.72

UltraTek HRP Anti-Polyvalent (DAB) Staining System
AMF080 70 Slides
EUR 70.71

SensiTek HRP Anti-Polyvalent (DAB) Staining System
AEM080 70 Slides
EUR 61.72

DAB Enhancer for ampliying and darkening DAB stains in IHC staining, 60 ml (Large volume)
NB308 60 ml
EUR 435

DAB Enhancer for ampliying and darkening DAB stains in IHC staining, 30 ml (Small volume)
NB308-30 30 ml
EUR 285

DAB Stable Liquid Substrate 50X Concentrate, 0.0694mM Staining System for HRPO
MBS639197-100mL 100mL
EUR 715

DAB Stable Liquid Substrate 50X Concentrate, 0.0694mM Staining System for HRPO
MBS639197-10mL 10mL
EUR 300

DAB Stable Liquid Substrate 50X Concentrate, 0.0694mM Staining System for HRPO
MBS639197-25mL 25mL
EUR 380

DAB Stable Liquid Substrate 50X Concentrate, 0.0694mM Staining System for HRPO
MBS639197-5x100mL 5x100mL
EUR 3075

STAT-Q Rabbit DAB KIT for staining all Rabbit antibodies, 350 plus slides
NB314KLRD-20 20 ml kit
EUR 645

STAT-Q Goat DAB KIT for staining all Goat primary antibodies, 350 plus slides
NB314KLGD-20 20 ml kit
EUR 645

PI Staining Kit
abx097208-1Kit 1 Kit
EUR 276

HE Staining Kit
E-IR-R117-100mL 100mL
EUR 240

HE Staining Kit
E-IR-R117-10mL 10mL
EUR 35

HE Staining Kit
E-IR-R117-50mL 50mL
EUR 150

HE Staining Kit
E-IR-R117-each each Ask for price

HE staining Kit
MBS2567140-100mL 100mL
EUR 255

HE staining Kit
MBS2567140-10mL 10mL
EUR 120

HE staining Kit
MBS2567140-50mL 50mL
EUR 195

HE staining Kit
MBS2567140-5x100mL 5x100mL
EUR 1120

PI Staining Kit
MBS826722-01mL 0.1mL
EUR 140

PI Staining Kit
MBS826722-5x01mL 5x0.1mL
EUR 550

DAPI Staining Kit
abx097206-100l 100 µl
EUR 162.5

DAPI Staining Kit
abx097206-1Kit 1 Kit
EUR 276

DAPI Staining Kit
abx097206-1ml 1 ml Ask for price

DAPI Staining Kit
abx097206-200l 200 µl Ask for price

TRAP Staining Kit
KT-008 1 kit
EUR 747

DAPI Staining Kit
MBS826728-01mL 0.1mL
EUR 140

DAPI Staining Kit
MBS826728-5x01mL 5x0.1mL
EUR 550

STAT-Q Rat Adsorbed DAB KIT for staining Mouse antibodies-on-Rat tissues 250 plus slides kit
NB314RAK-DAB 200-250 slides
EUR 745

Coplin Staining Jar
08415-3 3sets
EUR 93.96

Silver Staining Kit
ML123-1KT 1 unit
EUR 201.16
Description: Silver Staining Kit

STAT-Q Mouse Adsorbed DAB KIT for staining Rat antibodies-on-Mouse tissues 250 plus slide kit
NB314MAK-DAB 200-250 slides
EUR 695

DNA Staining Reagent
abx299713-100g 100 µg Ask for price

DNA Staining Reagent
abx299713-20g 20 µg
EUR 300

DNA Staining Reagent
abx299713-50g 50 µg Ask for price

Cell Staining Buffer
E-CK-A107-100mL 100 mL
EUR 20

Cell Staining Buffer
E-CK-A107-200mL 200 mL
EUR 35

Cell Staining Buffer
E-CK-A107-500mL 500 mL
EUR 60

Cell Staining Buffer
E-CK-A107-each each Ask for price

Cell Staining Buffer
E16FXP005 500 ml
EUR 40
Description: Available in various conjugation types.

Cell Staining Buffer
MBS2567126-100mL 100mL
EUR 90

Cell Staining Buffer
MBS2567126-200mL 200mL
EUR 100

Cell Staining Buffer
MBS2567126-500mL 500mL
EUR 125

Cell Staining Buffer
MBS2567126-5x500mL 5x500mL
EUR 545

Cell Staining Buffer
MBS679239-500mL 500mL
EUR 185

Cell Staining Buffer
MBS679239-5x500mL 5x500mL
EUR 675

Cell Staining Buffer
MBS679240-100mL 100mL
EUR 130

Cell Staining Buffer
MBS679240-5x100mL 5x100mL
EUR 435

Cell Staining Buffer
MBS679241-250mL 250mL
EUR 145

Cell Staining Buffer
MBS679241-5x250mL 5x250mL
EUR 515

DAPI Staining Solution
MBS176580-10mL 10mL
EUR 115

DAPI Staining Solution
MBS176580-50mL 50mL
EUR 135

DAPI Staining Solution
MBS176580-5x50mL 5x50mL
EUR 450

STAT-Q Multivalent DAB KIT for staining Mouse, Rat and Rabbit antibodies, 350 slides kit (Small size Kit)
NB314KLD-20 300 slide kit
EUR 655

jetBlue Protein Staining Solution
MBS402061-20mL 20mL
EUR 165

jetBlue Protein Staining Solution
MBS402061-500mL 500mL
EUR 210

Wright Staining Solution
K1182-100 100ml
EUR 40
Description: Cell Biology|Staining Solution

Wright Staining Solution
K1182-500 500ml
EUR 64
Description: Cell Biology|Staining Solution

STAT-Q Multivalent DAB KIT for staining Mouse, Rat and Rabbit antibodies, 1000 plus slides (Large size kit)
NB314KLD 1000 slides
EUR 895

ELVIS ID Staining Kit
SK-ELVIS-100 100 Tests Ask for price

ELVIS ID Staining Kit
SK-ELVIS-1000 1000 Tests Ask for price

ELVIS ID Staining Kit
SK-ELVIS-200 200 Tests Ask for price

ELVIS ID Staining Kit
SK-ELVIS-500 500 Tests Ask for price

Hoechst 33342 Staining Kit
abx097207-100l 100 µl
EUR 162.5

Hoechst 33342 Staining Kit
abx097207-1Kit 1 Kit
EUR 276

Hoechst 33342 Staining Kit
abx097207-1ml 1 ml Ask for price

Hoechst 33342 Staining Kit
abx097207-200l 200 µl Ask for price

Hoechst 33342 Staining Kit
MBS826727-01mL 0.1mL
EUR 140

Hoechst 33342 Staining Kit
MBS826727-5x01mL 5x0.1mL
EUR 550

Colloidal Protein Staining Solution
51581 100 ml
EUR 25.5
Description: Part B

Leishman Staining Solution
68015 250 ml
EUR 2.05
Description: Part A

DNA STAINING AGENT (1ML)
NOVELJUICE each
EUR 80

Hematoxylin Staining Buffer
E-IR-R120-15mL 15mL
EUR 60

Hematoxylin Staining Buffer
E-IR-R120-50mL 50mL
EUR 170

Hematoxylin Staining Buffer
E-IR-R120-5mL 5mL
EUR 25

Hematoxylin Staining Buffer
E-IR-R120-each each Ask for price

Cartilage Staining Solution
MBS355813-100mL 100mL
EUR 185

Cartilage Staining Solution
MBS355813-5x100mL 5x100mL
EUR 530

Hematoxylin staining Buffer
MBS2567138-15mL 15mL
EUR 125

Hematoxylin staining Buffer
MBS2567138-50mL 50mL
EUR 190

Hematoxylin staining Buffer
MBS2567138-5mL 5mL
EUR 95

Hematoxylin staining Buffer
MBS2567138-5x50mL 5x50mL
EUR 815

Cell Cycle Staining Kit
KTA2020-100T 100 T
EUR 119
Description: Abbkine Cell Cycle Staining Kit provides a convenient and accurate determination of the percentage of cells in each phase of the cell cycle.

Cell Cycle Staining Kit
KTA2020-50T 50 T
EUR 69
Description: Abbkine Cell Cycle Staining Kit provides a convenient and accurate determination of the percentage of cells in each phase of the cell cycle.

Cell Cycle Staining Kit
KTA2020-each each Ask for price

Cell Cycle Staining Kit
MBS9718793-100Tests 100Tests
EUR 225

Cell Cycle Staining Kit
MBS9718793-500Tests 500Tests
EUR 355

Cell Cycle Staining Kit
MBS9718793-50Tests 50Tests
EUR 195

Cell Cycle Staining Kit
MBS9718793-5x500Tests 5x500Tests
EUR 1580

HISTOCHEMISTRY STAINING TRAY
AT-12 12 PLACE - BLACK LID
EUR 226.1

HISTOCHEMISTRY STAINING TRAY
AT-24 24 PLACE - BLACK LID
EUR 342.21

HISTOCHEMISTRY STAINING TRAY
ATC-12 12 PLACE - CLEAR LID
EUR 226.1

HISTOCHEMISTRY STAINING TRAY
ATC-24 24 PLACE - CLEAR LID
EUR 342.21

Exosome fluorescent staining
S104 -
EUR 800

PI / RNase Staining Buffer
abx090619-100l 100 µl
EUR 162.5

PI / RNase Staining Buffer
20-abx090619
  • Ask for price
  • Ask for price
  • 50 tests
  • 100 tests

PI / RNase Staining Buffer
abx090619-1ml 1 ml Ask for price

PI / RNase Staining Buffer
abx090619-200l 200 µl
EUR 200

Live NucRed staining kit
EGY069 >100T
EUR 210

PI / RNase Staining Buffer
MBS355225-100Tests 100Tests
EUR 255

PI / RNase Staining Buffer
MBS355225-50Tests 50Tests
EUR 215

PI / RNase Staining Buffer
MBS355225-5x100Tests 5x100Tests
EUR 845

Live NucRed staining kit
MBS8584964-100Tests 100Tests
EUR 310

Live NucRed staining kit
MBS8584964-5x100Tests 5x100Tests
EUR 1405

Stains All Gel Staining Kit
KT-792 20 tests
EUR 737

EzWay Protein-Silver Staining Kit
K14040D 20A
EUR 188
Description: https://komabiotech.co.kr/labiskoma/datasheet/K14040D-korean.pdf

ProsiBlue Gel Staining Solution
P7300-050 500ml
EUR 102

7-AAD Staining Solution
MBS669126-200Tests 200Tests
EUR 145

7-AAD Staining Solution
MBS669126-5x200Tests 5x200Tests
EUR 655

Ponceau S Protein Staining Solution
PS003-B500ML 500 ml
EUR 25

Live NucGreen staining kit
EGY068 >100T
EUR 210

Dead NucGreen staining kit
EGY070 >100T
EUR 210

Live NucGreen staining kit
MBS8584963-100Tests 100Tests
EUR 310

Live NucGreen staining kit
MBS8584963-5x100Tests 5x100Tests
EUR 1405

Dead NucGreen staining kit
MBS8584965-100Tests 100Tests
EUR 310

Dead NucGreen staining kit
MBS8584965-5x100Tests 5x100Tests
EUR 1405

QUANTOMTx IQ/OQ Protocol
LBQ14001 each
EUR 991.9

GEL STAINING/INCUBATION BOX
SB-10 LIGHT SHIELDING
EUR 94.44

Ponceau S Staining Solution
41640009-1 500 mL
EUR 53.1

Ponceau S Staining Solution
41640009-2 1 L
EUR 76.5

Ponceau S Staining Solution
14092 100 ml
EUR 13.13
Description: Part B

Ponceau S Staining Solution
B7778-100000 100 g
EUR 77.6
Description: Others|Reagents

Ponceau S Staining Solution
B7778-50000 50 g
EUR 52.8
Description: Others|Reagents

Ponceau S Staining Solution
EZWB08-1x-100mL 100mL
EUR 9.6

Ponceau S Staining Solution
EZWB08-1x-500mL 500mL
EUR 32.4

SDS-PAGE Staining Solution
GR103068 100 mL
EUR 58

Giemsa Staining Solution (10X)
K1181-100 100ml
EUR 40
Description: Cell Biology|Staining Solution

Giemsa Staining Solution (10X)
K1181-500 500ml
EUR 64
Description: Cell Biology|Staining Solution

Ponceau S Staining Solution
MBS355693-100mL 100mL
EUR 180

Ponceau S Staining Solution
MBS355693-5x100mL 5x100mL
EUR 500

Sirius Red Staining Solution
MBS355815-100mL 100mL
EUR 195

Sirius Red Staining Solution
MBS355815-5x100mL 5x100mL
EUR 570

Ponceau S Staining Solution
PW005 100ml
EUR 82.97

AO/PI Double Staining Kit
K2238-100 100T
EUR 40
Description: Cell Biology|Cell Apoptosis

AO/PI Double Staining Kit
K2238-500 500T
EUR 120
Description: Cell Biology|Cell Apoptosis

Neutral Red Staining Solution
K1185-100 100ml
EUR 40
Description: Cell Biology|Staining Solution

EasyDip Slide Staining System
M900-12AS-ASSORTED 1 Case(s)
EUR 101.58

CellSurface FLOW Staining Kit
MBS668926-1Kit 1Kit
EUR 200

CellSurface FLOW Staining Kit
MBS668926-5x1Kit 5x1Kit
EUR 900

Dual- Color AP Staining Kit
AP100D-1 100 Assays
EUR 494.4

Propidium Iodide (PI) Staining Kit
abx097208-100l 100 µl
EUR 162.5

Propidium Iodide (PI) Staining Kit
abx097208-1ml 1 ml Ask for price

Propidium Iodide (PI) Staining Kit
abx097208-200l 200 µl Ask for price

CometAssay Silver Staining Kit
4254-200-K 200 Tests
EUR 390.96

Methyl Green Staining Solution
abx090698-100l 100 µl
EUR 125

Methyl Green Staining Solution
abx090698-1ml 1 ml Ask for price

Methyl Green Staining Solution
abx090698-200l 200 µl
EUR 187.5

β-Galactosidase Staining Kit
AKR-100 1 kit
EUR 288
Description: Excepted Quantities

PI Viability Staining Solution
E16FXP002 150 tests
EUR 40
Description: Available in various conjugation types.