Experimental Study of Shenfu Injection on the Prevention and Treatment of Paclitaxel Chemotherapy DRG Neuron Injury.

The function of this paper is investigating the impact and mechanism of Shenfu injection (a Traditional Chinese Medicine injection type) on prevention and therapy of paclitaxel chemotherapy in peripheral nerve harm.MethodsWistar rat dorsal root ganglion cells had been cultured in vitro and divided into teams of MOCK, PT, PT + LD, and PT + HD.

Each group was cultured at a complete serum focus of 10%, together with 10% clean serum in the MOCK group, 0.73 (IC30) μmol/L paclitaxel + 10% clean serum in the PT group, and 10% and 5% drug-containing serum and equal quantity of paclitaxel had been added into the high- and low-dosage teams, respectively.

After culturing for 24 hours, the following checks had been carried out: (1) cell proliferation detected by utilizing CCK-8 and a microplate reader; (2) axon size detected by mobile immunostaining and detection evaluation on antibody β-tubulin III; and (3) modifications in mitochondrial membrane potential by analyzing immunofluorescence staining with JC-1 probe.

Results(1) Cell proliferation: OD values of the MOCK group and PT group had been 0.43 ± 0.02 and 0.25 ± 0.03, respectively (P < 0.05), whereas OD values of teams PT + LD and PT + HD had been 0.41 ± 0.05 and 0.46 ± 0.03, respectively, larger than group PT (P < 0.05), whereas OD values of teams PT + LD and PT + HD had been 0.41 ± 0.05 and 0.46 ± 0.03, respectively, larger than group PT (μmol/L paclitaxel + 10% clean serum in the PT group, and 10% and 5% drug-containing serum and equal quantity of paclitaxel had been added into the high- and low-dosage teams, respectively.

Experimental Study of Shenfu Injection on the Prevention and Treatment of Paclitaxel Chemotherapy DRG Neuron Injury.
Experimental Study of Shenfu Injection on the Prevention and Treatment of Paclitaxel Chemotherapy DRG Neuron Injury.

After culturing for 24 hours, the following checks had been carried out: (1) cell proliferation detected by utilizing CCK-8 and a microplate reader; (2) axon size detected by mobile immunostaining and detection evaluation on antibody μmol/L paclitaxel + 10% clean serum in the PT group, and 10% and 5% drug-containing serum and equal quantity of paclitaxel had been added into the high- and low-dosage teams, respectively.

Test for Identify Legionella.p

MIC6772 PK50
EUR 266.76

Human TES(Testin) ELISA Kit

EH1738 96T
EUR 681.12
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 0.375 ng/ml

T(Testosterone) ELISA Kit

EU0400 96T
EUR 571.5
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: General;Sensitivity: 0.188 ng/ml

Mouse Testosterone ELISA Kit

EM1850 96T
EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Mus ;Sensitivity: 0.188 ng/ml

Human Testosterone ELISA Kit

EH4850 96T
EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens ;Sensitivity: 0.188 ng/ml

Rat T(Testosterone) ELISA Kit

ER1462 96T
EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Rattus;Sensitivity: 0.188 ng/ml

Test for Identif of Staph.a

MIC6766 PK100
EUR 91.2

Test for Identif of Staph.a

MIC6768 PK500
EUR 311.22

Bovine T(Testosterone) ELISA Kit

EB0049 96T
EUR 681.12
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Cattle;Sensitivity: 0.188 ng/ml

Human SPOCK2(Testican-2) ELISA Kit

EH2271 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Test for Identifi of Listeria

MIC6778 PK50
EUR 119.7

Test for Identi of Clostridium.d

MIC6762 PK50
EUR 183.54

Test for Identi of Salmonellae

MIC6764 PK50
EUR 139.08

Test for Identifying E.coli O157

MIC6770 PK50
EUR 78.66

TESTO (Testosterone) ELISA test

19 96T/Box Ask for price
Description: ELISA based test for quantitative detection of O (osterone)

Human TEX101(testis expressed 101) ELISA Kit

EH12903 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens ;Sensitivity: 0.188 ng/ml

Human F-TESTO(Free Testoterone) ELISA Kit

EH3092 96T
EUR 571.5
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Test Tube Rack Holder (for 50 Ml Test Tube Racks)

480169 EACH
EUR 58.8

Test tube tray for OLS26

BAT1066 EACH
EUR 285.6

Test tube tray for LSB12

BAT1068 EACH
EUR 271.2

Test tube tray for LSB18

BAT1070 EACH
EUR 285.6

Test for Strep groups ABCDF&G

MIC6776 PK50
EUR 167.58

NOVATest Antigen Rapid Test Kit (For Single Use) (NOVA Test)

nCov-500-01 1T
EUR 162

CA72-4 ELISA test

24 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CA72-4

PreS2-Ag ELISA test

96 96T/Box Ask for price
Description: ELISA based test for quantitative detection of PreS2-Ag

1-hour Dog meat adulteration ELISA test (for beef or pig meat; 96 tests)

DMT-96 1 kit
EUR 1000.8

1-hour Rat meat adulteration ELISA test (for beef or pig meat; 96 tests)

RMT-96 1 kit
EUR 1000.8

Rat Pdha2(Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial) ELISA Kit

ER0417 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 46.9pg/ml

Human PDHA2(Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial) ELISA Kit

EH1149 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

T4 (Thyroxine) ELISA test

16 96T/Box Ask for price
Description: ELISA based test for quantitative detection of T4 (Thyroxine)

E2 (Estradiol) ELISA test

5 96T/Box Ask for price
Description: ELISA based test for quantitative detection of E2 (Estradiol)

PRL (Prolactin) ELISA test

4 96T/Box Ask for price
Description: ELISA based test for quantitative detection of PRL (Prolactin)

FERR ( Ferritin) ELISA test

7 96T/Box Ask for price
Description: ELISA based test for quantitative detection of FERR ( Ferritin)

HBcAb Sandwich ELISA test

95 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HBcAb Sandwich

TSH (Thyrotrophin) ELISA test

14 96T/Box Ask for price
Description: ELISA based test for quantitative detection of TSH (Thyrotrophin)

Pipette for Card Test 70mm 1ml

BSV150 PK10000
EUR 302.4

Syphilis Antibody ELISA test

100 96T/Box Ask for price
Description: ELISA based test for quantitative detection of Syphilis Antibody

PROG (Progesterone) ELISA test

20 96T/Box Ask for price
Description: ELISA based test for quantitative detection of PROG (Progesterone)

12 Test System for Neg Bacteria

MIC6708 PK24
EUR 110.58

1-hour Beef/Cow meat adulteration ELISA test (for beef or pig meat; 96 tests)

BMT-96 1 kit
EUR 1000.8

T3 (Triiodothyronine) ELISA test

15 96T/Box Ask for price
Description: ELISA based test for quantitative detection of T3 (Triiodothyronine)

1-hour Horse/Donkey meat adulteration ELISA test (for beef or pig meat; 96 tests)

HMT-96 1 Kit
EUR 1000.8

Kinesis Siltite Micron union Re order 0.8-0.8 does not include ferrules

CHR1933 EACH
EUR 194.4

Mouse LAT(Linker for activation of T cell) ELISA Kit

EM1183 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

1-hour Pig meat adulteration ELISA test (for beef or pig meat; 96 tests), Quantitative

PMT-96 1 kit
EUR 1000.8

Human LAT(Linker For Activation of T-cell) ELISA Kit

EH3288 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

SS test tube rack for 30 tubes

BAT8158 EACH
EUR 126

SS test tube rack for 42 tubes

BAT8159 EACH
EUR 130.8

SS test tube rack for 42 tubes

BAT8160 EACH
EUR 126

HAV antibody IgM ELISA test

75 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HAV antibody IgM

HEV antibody IgM ELISA test

92 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HEV antibody IgM

QUANTOFIX ASCORBIC-ACID TEST STICKS FOR

Z166340-100EA EACH
EUR 54

FT4 (Free thyroxine) ELISA test

18 96T/Box Ask for price
Description: ELISA based test for quantitative detection of FT4 (Free thyroxine)

CEA (Cancer antigen) ELISA test

9 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CEA (Cancer antigen)

CA50 (Cancer antigen) ELISA test

10 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CA50 (Cancer antigen)

CA199 (Cancer antigen) ELISA test

13 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CA199 (Cancer antigen)

CA153 (Cancer antigen) ELISA test

12 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CA153 (Cancer antigen)

CA125 (Cancer antigen) ELISA test

11 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CA125 (Cancer antigen)

Tetrodotoxin (TTX) ELISA Test Kit

DEIANJ48 96T
EUR 1950
Description: This test kit is for the quantitative detection of Tetrodotoxin in the tissue, liver, fish.

plastic test tube rack for 60 tubes

BAT8155 EACH
EUR 78

plastic test tube rack for 90 tubes

BAT8156 EACH
EUR 78

plastic test tube rack for 21 tubes

BAT8157 EACH
EUR 78

Human CD32(Receptor II for the Fc Fragment of IgG) ELISA Kit

EH0083 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 28.125pg/ml

AFP (Alpha fetoprotein) ELISA test

6 96T/Box Ask for price
Description: ELISA based test for quantitative detection of AFP (Alpha fetoprotein)

LH (Luteinizing Hormone) ELISA test

2 96T/Box Ask for price
Description: ELISA based test for quantitative detection of LH (Luteinizing Hormone)

Human DR-70TM(Tumor Marker DR-70 For Lung Cancer) ELISA Kit

EH2961 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ug/ml

Test Tube Rack Holder (for 15 Ml Test Tube Racks) Fits I-5330 Platform

480168 EACH
EUR 58.8

Rat sRAGE(Solube Receptor for Advanced Glycation End product) ELISA Kit

ER1853 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 46.875pg/ml

Human sRAGE(Solube Receptor for Advanced Glycation End product) ELISA Kit

EH0408 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

FT3 (Free triiodothyronine) ELISA test

17 96T/Box Ask for price
Description: ELISA based test for quantitative detection of FT3 (Free triiodothyronine)

Test kit for Potential Anti Oxidant (PAO)

LF-EK90001 1x96T
EUR 1050

Test Tube rack for 40 x 0.5mL tubes

BAT3018 EACH
EUR 136.8

Human CD23(Receptor II for the Fc Region of Immunoglobulin E) ELISA Kit

EH0079 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Test Tube rack for 41 x 15mL tubes

BAT3070 EACH
EUR 145.2

Test Tube rack for 15 x 50mL tubes

BAT3072 EACH
EUR 145.2

Test Tube rack for 76 x 15mL tubes

BAT3074 EACH
EUR 289.2

Test Tube rack for 30 x 50mL tubes

BAT3076 EACH
EUR 289.2

CYFRA211 (Keratin 21-1) ELISA test

23 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CYFRA211 (Keratin 21-1)

HIV 1+2 Ab CE ELISA test

97 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HIV 1+2 Ab CE

HIV 1+2 Ag/Ab ELISA test

98 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HIV 1+2 Ag/Ab

IgE (Immune globulin E) ELISA test

21 96T/Box Ask for price
Description: ELISA based test for quantitative detection of IgE (Immune globulin)

SS test tube rack for 10 Falcon tubes

BAT8161 EACH
EUR 126

Human FcγR I(Receptor I for the Fc Region of Immunoglobulin G) ELISA Kit

EH3046 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml

RV (Rubella Antibody IgM) ELISA test

31 96T/Box Ask for price
Description: ELISA based test for quantitative detection of RV (Rubella Antibody IgM)

RV (Rubella Antibody IgG) ELISA test

30 96T/Box Ask for price
Description: ELISA based test for quantitative detection of RV (Rubella Antibody IgG)

Human esRAGE(Endogenous secretory Receptor for Advanced Glycation End product) ELISA Kit

EH2885 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.4pg/ml

Rat MTL5(Tesmin) ELISA Kit

ER1521 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 18.75pg/ml

ACA Anticardiolipin Ab IgA ELISA test

122 96T/Box Ask for price
Description: ELISA based test for quantitative detection of ACA Anticardiolipin Ab IgA

IAA (Anti-insulin antibody) ELISA test

25 96T/Box Ask for price
Description: ELISA based test for quantitative detection of IAA (Anti-insulin antibody)

Adv (Adenovirus Antibody IgM) ELISA test

44 96T/Box Ask for price
Description: ELISA based test for quantitative detection of Adv (Adenovirus Antibody IgM)

TOX (Toxoplasma Antibody IgM) ELISA test

33 96T/Box Ask for price
Description: ELISA based test for quantitative detection of TOX (Toxoplasma Antibody IgM)

TOX (Toxoplasma Antibody IgG) ELISA test

32 96T/Box Ask for price
Description: ELISA based test for quantitative detection of TOX (Toxoplasma Antibody IgG)

Syphilis anti-TP syphilis ELISA test

99 96T/Box Ask for price
Description: ELISA based test for quantitative detection of Syphilis anti-TP syphilis

Test Tube rack for 41 x 15 ml tubes

B2000-4-T150 1 each
EUR 109.3

Test Tube rack for 40 x 0.5 ml tubes

B2000-4-T5 1 PC
EUR 101.9

Test Tube rack for 15 x 50 ml tubes

B2000-4-T500 1 each
EUR 109.3

Test Tube rack for 76 x 15 ml tubes

B2000-8-T150 1 each
EUR 219.7

Test Tube rack for 30 x 50 ml tubes

B2000-8-T500 1 each
EUR 219.7

Test Tube rack for 15 x 50 ml tubes

 -B2000-4-T500 1 PC
EUR 252.35

Test Tube rack for 41 x 15 ml tubes

  B2000-4-T150 1 PC
EUR 164.65

Test Tube rack for 76 x 15 ml tubes

  B2000-8-T150 1 PC
EUR 252.35

Test Tube rack for 30 x 50 ml tubes

  B2000-8-T500 1 PC
EUR 2995.98

Standard Test Slide for QuadCount, pk of 1  

E7500-STS1 1 each
EUR 280.9

ANA (Antinuclear Antibody IgG) ELISA test

52 96T/Box Ask for price
Description: ELISA based test for quantitative detection of ANA (Antinuclear Antibody IgG)

Test Tube rack for 40 x 1.5/2.0mL tubes

BAT3048 EACH
EUR 128.4

ASA Anti-sperm Ab IgG ELISA test

118 96T/Box Ask for price
Description: ELISA based test for quantitative detection of ASA Anti-sperm Ab IgG

COX (Coxsackievirus Antibody IgG) ELISA test

140 96T/Box Ask for price
Description: ELISA based test for quantitative detection of COX (Coxsackievirus Antibody IgG)

COX (Coxsackievirus Antibody IgM) ELISA test

141 96T/Box Ask for price
Description: ELISA based test for quantitative detection of COX (Coxsackievirus Antibody IgM)

PSA (Prostate-specific antigen) ELISA test

8 96T/Box Ask for price
Description: ELISA based test for quantitative detection of PSA (Prostate-specific antigen)

Porcine Parvovirus Antibody Elisa Test Kit

767-LSY-30009 192 Wells/kit
EUR 382

?-HCG (Human chorionic gonadotropin) ELISA test

1 96T/Box Ask for price
Description: ELISA based test for quantitative detection of ?-HCG (Human chorionic gonadotropin)

HGH (Human chorionic gonadotropin) ELISA test

22 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HGH (Human chorionic gonadotropin)

CMV (Cytomegalovirus Antibody IgG) ELISA test

28 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CMV (Cytomegalovirus Antibody IgG)

ACA (Anticardiolipin Antibody IgA) ELISA test

61 96T/Box Ask for price
Description: ELISA based test for quantitative detection of ACA (Anticardiolipin Antibody IgA)

ACA (Anticardiolipin Antibody IgM) ELISA test

60 96T/Box Ask for price
Description: ELISA based test for quantitative detection of ACA (Anticardiolipin Antibody IgM)

ACA (Anticardiolipin Antibody IgG) ELISA test

59 96T/Box Ask for price
Description: ELISA based test for quantitative detection of ACA (Anticardiolipin Antibody IgG)

CMV (Cytomegalovirus Antibody IgM) ELISA test

29 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CMV (Cytomegalovirus Antibody IgM)

HCV-IgM hepatitis C IgM ELISA test

87 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HCV-IgM hepatitis C IgM

HDV-IgG hepatitis D IgG ELISA test

88 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HDV-IgG hepatitis D IgG

HDV-IgM hepatitis D IgM ELISA test

89 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HDV-IgM hepatitis D IgM

After culturing for 24 hours, the following checks had been carried out: (1) cell proliferation detected by utilizing CCK-8 and a microplate reader; (2) axon size detected by mobile immunostaining and detection evaluation on antibody P < 0.05), whereas OD values of groups PT + LD and PT + HD had been 0.41 ± 0.05 and 0.46 ± 0.03, respectively, larger than group PT (P < 0.05), whereas OD values of teams PT + LD and PT + HD had been 0.41 ± 0.05 and 0.46 ± 0.03, respectively, larger than group PT (.Shenfu injection can forestall the toxicity of DRG neurons induced by paclitaxel, and its mechanism could also be associated to the alleviation of mitochondrial dysfunction.

Leave a Reply

Your email address will not be published.