Experimental Study of Shenfu Injection on the Prevention and Treatment of Paclitaxel Chemotherapy DRG Neuron Injury.

The function of this paper is investigating the impact and mechanism of Shenfu injection (a Traditional Chinese Medicine injection type) on prevention and therapy of paclitaxel chemotherapy in peripheral nerve harm.MethodsWistar rat dorsal root ganglion cells had been cultured in vitro and divided into teams of MOCK, PT, PT + LD, and PT + HD.

Each group was cultured at a complete serum focus of 10%, together with 10% clean serum in the MOCK group, 0.73 (IC30) μmol/L paclitaxel + 10% clean serum in the PT group, and 10% and 5% drug-containing serum and equal quantity of paclitaxel had been added into the high- and low-dosage teams, respectively.

After culturing for 24 hours, the following checks had been carried out: (1) cell proliferation detected by utilizing CCK-8 and a microplate reader; (2) axon size detected by mobile immunostaining and detection evaluation on antibody β-tubulin III; and (3) modifications in mitochondrial membrane potential by analyzing immunofluorescence staining with JC-1 probe.

Results(1) Cell proliferation: OD values of the MOCK group and PT group had been 0.43 ± 0.02 and 0.25 ± 0.03, respectively (P < 0.05), whereas OD values of teams PT + LD and PT + HD had been 0.41 ± 0.05 and 0.46 ± 0.03, respectively, larger than group PT (P < 0.05), whereas OD values of teams PT + LD and PT + HD had been 0.41 ± 0.05 and 0.46 ± 0.03, respectively, larger than group PT (μmol/L paclitaxel + 10% clean serum in the PT group, and 10% and 5% drug-containing serum and equal quantity of paclitaxel had been added into the high- and low-dosage teams, respectively.

Experimental Study of Shenfu Injection on the Prevention and Treatment of Paclitaxel Chemotherapy DRG Neuron Injury.
Experimental Study of Shenfu Injection on the Prevention and Treatment of Paclitaxel Chemotherapy DRG Neuron Injury.

After culturing for 24 hours, the following checks had been carried out: (1) cell proliferation detected by utilizing CCK-8 and a microplate reader; (2) axon size detected by mobile immunostaining and detection evaluation on antibody μmol/L paclitaxel + 10% clean serum in the PT group, and 10% and 5% drug-containing serum and equal quantity of paclitaxel had been added into the high- and low-dosage teams, respectively.

Test for Identi of Clostridium.d

MIC6762 PK50
EUR 183.54

Test for Identi of Salmonellae

MIC6764 PK50
EUR 139.08

Test for Identif of Staph.a

MIC6766 PK100
EUR 91.2

Test for Identif of Staph.a

MIC6768 PK500
EUR 311.22

Test for Identifying E.coli O157

MIC6770 PK50
EUR 78.66

Test for Identifi of Listeria

MIC6778 PK50
EUR 119.7

Test tube tray for OLS26

BAT1066 EACH
EUR 250.8

Test tube tray for LSB12

BAT1068 EACH
EUR 238.26

Test tube tray for LSB18

BAT1070 EACH
EUR 250.8

Test Tube Rack Holder (for 50 Ml Test Tube Racks)

480169 EACH
EUR 53.35

NOVATest Antigen Rapid Test Kit (For Single Use) (NOVA Test)

nCov-500-01 1T
EUR 162

12 Test System for Neg Bacteria

MIC6708 PK24
EUR 110.58

Test for Strep groups ABCDF&G

MIC6776 PK50
EUR 167.58

Pipette for Card Test 70mm 1ml

BSV150 PK10000
EUR 263.34

QUANTOFIX ASCORBIC-ACID TEST STICKS FOR

Z166340-100EA EACH
EUR 51.3

FERR ( Ferritin) ELISA test

7 96T/Box Ask for price
Description: ELISA based test for quantitative detection of FERR ( Ferritin)

PRL (Prolactin) ELISA test

4 96T/Box Ask for price
Description: ELISA based test for quantitative detection of PRL (Prolactin)

E2 (Estradiol) ELISA test

5 96T/Box Ask for price
Description: ELISA based test for quantitative detection of E2 (Estradiol)

CA72-4 ELISA test

24 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CA72-4

PROG (Progesterone) ELISA test

20 96T/Box Ask for price
Description: ELISA based test for quantitative detection of PROG (Progesterone)

TESTO (Testosterone) ELISA test

19 96T/Box Ask for price
Description: ELISA based test for quantitative detection of O (osterone)

TSH (Thyrotrophin) ELISA test

14 96T/Box Ask for price
Description: ELISA based test for quantitative detection of TSH (Thyrotrophin)

T3 (Triiodothyronine) ELISA test

15 96T/Box Ask for price
Description: ELISA based test for quantitative detection of T3 (Triiodothyronine)

T4 (Thyroxine) ELISA test

16 96T/Box Ask for price
Description: ELISA based test for quantitative detection of T4 (Thyroxine)

Syphilis Antibody ELISA test

100 96T/Box Ask for price
Description: ELISA based test for quantitative detection of Syphilis Antibody

HBcAb Sandwich ELISA test

95 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HBcAb Sandwich

Accu-Tell COVID-19 IgG/IgM Rapid Test

GEN-B352-20tests 20 tests
EUR 283.2
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Accu-Tell COVID-19 IgG/IgM Rapid Test

GEN-B352-40tests 40 tests
EUR 385.2
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Test kit for Potential Anti Oxidant (PAO)

LF-EK90001 1x96T
EUR 1050

plastic test tube rack for 60 tubes

BAT8155 EACH
EUR 74.1

plastic test tube rack for 90 tubes

BAT8156 EACH
EUR 74.1

plastic test tube rack for 21 tubes

BAT8157 EACH
EUR 74.1

SS test tube rack for 30 tubes

BAT8158 EACH
EUR 119.7

SS test tube rack for 42 tubes

BAT8159 EACH
EUR 124.26

SS test tube rack for 42 tubes

BAT8160 EACH
EUR 119.7

Test product

testtt 0 Ask for price

Tetrodotoxin (TTX) ELISA Test Kit

DEIANJ48 96T
EUR 1950
Description: This test kit is for the quantitative detection of Tetrodotoxin in the tissue, liver, fish.

HAV antibody IgM ELISA test

75 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HAV antibody IgM

AFP (Alpha fetoprotein) ELISA test

6 96T/Box Ask for price
Description: ELISA based test for quantitative detection of AFP (Alpha fetoprotein)

HEV antibody IgM ELISA test

92 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HEV antibody IgM

LH (Luteinizing Hormone) ELISA test

2 96T/Box Ask for price
Description: ELISA based test for quantitative detection of LH (Luteinizing Hormone)

FT4 (Free thyroxine) ELISA test

18 96T/Box Ask for price
Description: ELISA based test for quantitative detection of FT4 (Free thyroxine)

CA125 (Cancer antigen) ELISA test

11 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CA125 (Cancer antigen)

FT3 (Free triiodothyronine) ELISA test

17 96T/Box Ask for price
Description: ELISA based test for quantitative detection of FT3 (Free triiodothyronine)

CA50 (Cancer antigen) ELISA test

10 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CA50 (Cancer antigen)

CA153 (Cancer antigen) ELISA test

12 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CA153 (Cancer antigen)

CA199 (Cancer antigen) ELISA test

13 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CA199 (Cancer antigen)

CEA (Cancer antigen) ELISA test

9 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CEA (Cancer antigen)

Test Tube Rack Holder (for 15 Ml Test Tube Racks) Fits I-5330 Platform

480168 EACH
EUR 53.35

Test Tube rack for 40 x 0.5mL tubes

BAT3018 EACH
EUR 112.86

Test Tube rack for 41 x 15mL tubes

BAT3070 EACH
EUR 120.84

Test Tube rack for 15 x 50mL tubes

BAT3072 EACH
EUR 120.84

Test Tube rack for 76 x 15mL tubes

BAT3074 EACH
EUR 240.54

Test Tube rack for 30 x 50mL tubes

BAT3076 EACH
EUR 240.54

SS test tube rack for 10 Falcon tubes

BAT8161 EACH
EUR 119.7

2019-nCoV IgG/IgM Rapid Test Cassette (Whole Blood/Serum/Plasma)

GEN-402-25tests 25 tests
EUR 292.8
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

DNASE TEST AGAR

D04-101-10kg 10 kg Ask for price

DNASE TEST AGAR

D04-101-2Kg 2 Kg Ask for price

DNASE TEST AGAR

D04-101-500g 500 g Ask for price

DERMATOPHYTE TEST AGAR

D04-107-10kg 10 kg
EUR 1018.8

DERMATOPHYTE TEST AGAR

D04-107-2Kg 2 Kg
EUR 268.8

DERMATOPHYTE TEST AGAR

D04-107-500g 500 g
EUR 116.4

MOTILITY TEST MEDIUM

M13-121-10kg 10 kg
EUR 1833.6

MOTILITY TEST MEDIUM

M13-121-2Kg 2 Kg
EUR 445.2

MOTILITY TEST MEDIUM

M13-121-500g 500 g
EUR 164.4

SNYDER TEST AGAR

S19-119-10kg 10 kg
EUR 1258.8

SNYDER TEST AGAR

S19-119-2Kg 2 Kg
EUR 320.4

SNYDER TEST AGAR

S19-119-500g 500 g
EUR 130.8

SAM Test Strip

TS00201s-30 30 tests
EUR 499.2
Description: S-adenosylmethionine quantitative test strip for serum, plasma and whole blood

SAH Test Strip

TS00301s-30 30 tests
EUR 604.8
Description: S-adenosylhomocysteine quantitative test strip for serum, plasma and whole blood

HCY Test Strip

TS00401s-30 30 tests
EUR 663.6
Description: Serum homocysteine quantitative test strip

Phenols Cuvette Test

LCK345 EACH
EUR 141.72

Dermatophyte Test Medium

MED1484 EACH
EUR 87.78

Sulphite Test Strips

MN91306 PK100
EUR 51.53

Thermal Test Film

PCR0890 PK25
EUR 383.04

Dryslide Oxidase Test

231746 PK75
EUR 199.5

Test Tube 16x100mm

3840/16X100 PK100
EUR 57.11

aa test product

123 1MG
EUR 279.6

5mL Test Tubes

TUB0228 PK1400
EUR 159.6

Spectroquant COD test

WAT1080 EACH
EUR 96.9

Phosphate Total Test

WAT3655 EACH
EUR 203.01

Holder for Plasmid Midi, Maxi and Maxi plus, Ion Exchange column

FAPDE-holder-for-ion-exchange 1 prep
EUR 189.6

TOX (Toxoplasma Antibody IgG) ELISA test

32 96T/Box Ask for price
Description: ELISA based test for quantitative detection of TOX (Toxoplasma Antibody IgG)

ACA (Anticardiolipin Antibody IgM) ELISA test

60 96T/Box Ask for price
Description: ELISA based test for quantitative detection of ACA (Anticardiolipin Antibody IgM)

ANA (Antinuclear Antibody IgG) ELISA test

52 96T/Box Ask for price
Description: ELISA based test for quantitative detection of ANA (Antinuclear Antibody IgG)

ACA (Anticardiolipin Antibody IgA) ELISA test

61 96T/Box Ask for price
Description: ELISA based test for quantitative detection of ACA (Anticardiolipin Antibody IgA)

IgE (Immune globulin E) ELISA test

21 96T/Box Ask for price
Description: ELISA based test for quantitative detection of IgE (Immune globulin)

HGH (Human chorionic gonadotropin) ELISA test

22 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HGH (Human chorionic gonadotropin)

Adv (Adenovirus Antibody IgM) ELISA test

44 96T/Box Ask for price
Description: ELISA based test for quantitative detection of Adv (Adenovirus Antibody IgM)

CYFRA211 (Keratin 21-1) ELISA test

23 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CYFRA211 (Keratin 21-1)

IAA (Anti-insulin antibody) ELISA test

25 96T/Box Ask for price
Description: ELISA based test for quantitative detection of IAA (Anti-insulin antibody)

RV (Rubella Antibody IgM) ELISA test

31 96T/Box Ask for price
Description: ELISA based test for quantitative detection of RV (Rubella Antibody IgM)

RV (Rubella Antibody IgG) ELISA test

30 96T/Box Ask for price
Description: ELISA based test for quantitative detection of RV (Rubella Antibody IgG)

TOX (Toxoplasma Antibody IgM) ELISA test

33 96T/Box Ask for price
Description: ELISA based test for quantitative detection of TOX (Toxoplasma Antibody IgM)

CMV (Cytomegalovirus Antibody IgG) ELISA test

28 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CMV (Cytomegalovirus Antibody IgG)

CMV (Cytomegalovirus Antibody IgM) ELISA test

29 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CMV (Cytomegalovirus Antibody IgM)

COX (Coxsackievirus Antibody IgG) ELISA test

140 96T/Box Ask for price
Description: ELISA based test for quantitative detection of COX (Coxsackievirus Antibody IgG)

COX (Coxsackievirus Antibody IgM) ELISA test

141 96T/Box Ask for price
Description: ELISA based test for quantitative detection of COX (Coxsackievirus Antibody IgM)

?-HCG (Human chorionic gonadotropin) ELISA test

1 96T/Box Ask for price
Description: ELISA based test for quantitative detection of ?-HCG (Human chorionic gonadotropin)

ACA Anticardiolipin Ab IgA ELISA test

122 96T/Box Ask for price
Description: ELISA based test for quantitative detection of ACA Anticardiolipin Ab IgA

Syphilis anti-TP syphilis ELISA test

99 96T/Box Ask for price
Description: ELISA based test for quantitative detection of Syphilis anti-TP syphilis

PSA (Prostate-specific antigen) ELISA test

8 96T/Box Ask for price
Description: ELISA based test for quantitative detection of PSA (Prostate-specific antigen)

Porcine Parvovirus Antibody Elisa Test Kit

767-LSY-30009 192 Wells/kit
EUR 382

Test Tube rack for 15 x 50 ml tubes

 -B2000-4-T500 1 PC
EUR 252.35

Test Tube rack for 41 x 15 ml tubes

  B2000-4-T150 1 PC
EUR 164.65

Test Tube rack for 76 x 15 ml tubes

  B2000-8-T150 1 PC
EUR 252.35

Test Tube rack for 30 x 50 ml tubes

  B2000-8-T500 1 PC
EUR 2995.98

Test Tube rack for 40 x 0.5 ml tubes

B2000-4-T5 1 PC
EUR 153.17

Eppendorf Mixmate Tube Holder For 0.5ml Micro Test Tubes

E5353040121 EACH
EUR 100.32

Test Tube rack for 40 x 1.5/2.0mL tubes

BAT3048 EACH
EUR 106.02

NOVATest IgG/IgM Antibody Rapid Test Kit (NOVA Test)

UNCOV-40 40 Tests
EUR 115

Basic Cytotoxicity Test Kits

CT17001 125 Tests
EUR 490.8

Basic Cytotoxicity Test Kits

CT17002 250 Tests
EUR 780

Total Cytotoxicity Test Kits

CT17003 125 Tests
EUR 615.6

Total Cytotoxicity Test Kits

CT17004 250 Tests
EUR 975.6

Clearview Chlamydia MF test

CV504524 1 box
EUR 194.4
Description: Please check the datasheet of Clearview Chlamydia MF test before using the test.

Melamine Rapid Test Kit

abx092011-50tests 50 tests
EUR 444

NDV rapid test kit

RG15-03 1 box
EUR 166.86
Description: Please check the datasheet of NDV rapid test kit before using the test.

IBD rapid test strip

RG15-04 10 boxes
EUR 177.6
Description: Please check the datasheet of IBD rapid test strip before using the test.

Rabies rapid test strip

RG18-01 10 boxes
EUR 182.3
Description: Please check the datasheet of Rabies rapid test strip before using the test.

After culturing for 24 hours, the following checks had been carried out: (1) cell proliferation detected by utilizing CCK-8 and a microplate reader; (2) axon size detected by mobile immunostaining and detection evaluation on antibody P < 0.05), whereas OD values of groups PT + LD and PT + HD had been 0.41 ± 0.05 and 0.46 ± 0.03, respectively, larger than group PT (P < 0.05), whereas OD values of teams PT + LD and PT + HD had been 0.41 ± 0.05 and 0.46 ± 0.03, respectively, larger than group PT (.Shenfu injection can forestall the toxicity of DRG neurons induced by paclitaxel, and its mechanism could also be associated to the alleviation of mitochondrial dysfunction.

Leave a Reply

Your email address will not be published.